The study of chemistry is quite interesting because of the different scientific structures that are involved.

When talking of synthetic organic chemistry, you are likely to come across different organic compounds and organic materials being combined together. Therefore synthetic organic chemistry is simply the scientific study of the merging of different structures, properties and reactions of an organic compound.

On the other hand synthetic organic chemistry can be defined as the artificial preparation of organic compounds or organic materials in the laboratory. Expert pharmacists can also describe it as the synthesis of organic compounds through laboratory procedures and experiments.

There are so many chemical compounds that have been used in synthetic organic chemistry. Some of these compounds include hydrocarbons, radio stable elements of halogens, and myriad whose main composition is based on carbons but also has other elements.

Many pharmaceutical organizations have invested in state of the art laboratories, so as to enable proper synthesis of organic compounds used in the production of drugs. The complexity that accompanies the synthesis of organic compounds needs organizations that are willing and ready to abide by all rules and regulations that govern the pharmaceutical industry at large. Unlike natural organic compounds, synthetic organic compounds do not occur naturally, they are acquired through a steady and thorough combination of different compounds and properties.

As we have seen above, synthetic organic chemistry needs a lot of expertise and experience. Intense research has to be carried out on different naturally occurring compounds and scientifically manufactured compounds.

Many pharmacists around the globe need to attend many training seminars so as to understand the nature and changing behaviour of organic compounds. Chemistry is usually not a hard subject to understand. It only needs thorough studies, research and practise. Of you do not practice chemistry, then you will not understand the behaviour and nature of different compounds.




For you to comprehend the idea of synthetic organic chemistry, you need the fundamental learning of natural science, ideal from its definition.

Well simply like in natural science, synthetic organic chemistry additionally concentrates on the component carbon. This is on account of carbon is the inside point to all living beings with life.

In the investigation of synthetic organic chemistry, we generally major our emphasis on the mix of various mixes in an exertion gone for thinking of various ones. Carbon’s awesome capacity of having firmly pressed particles makes it an extremely extraordinary basic component. This rule makes it sufficiently liberal to bond with a few different mixes.

While contemplating science, synthetic organic chemistry will dependably continue to be a part of great pharmaceutical studies. While digesting this fact, you will understand that atoms that have comparable properties are typically assembled together. The properties are typically partitioned into two that is physical and compound properties.

Numerous pharmaceutical associations additionally make great utilization of manufactured natural science material. This is on the grounds that they require more learning, aptitude, and ability in this area in order to think of top notch pharmaceuticals. Regardless of the complexities joined by the investigation of natural science, it is imperative that the subject is taken care of genuinely. On the off chance that diverse mixes are not all around joined, or if there is a wrong mix of components, there is a probability of a hurtful part being made, rather than a therapeutic medication. That is the reason standards, laws and directions have been passed by government medicinal offices to represent this industry. There is one pharmaceutical organization in India that was restricted as a result of neglecting to consent by the assembling controls. They were controlling their lab tests. This was accomplished for the benefit of the overall population and patients on the loose.



The pharmaceutical business has developed enormously on account of various reason.

of the reasons being the help by government and non-legislative offices, quick monetary development and the most imperative of all is the enhanced condition of research centres utilized for synthetic organic chemistry and fabricate of medications.

Numerous drug specialists have a tremendous information in synthetic organic chemistry, and this is a positive pointer that the pharmaceutical business is moving a step higher. Auxiliary schools and colleges majoring in the investigation of medication have amended their syllabi and made it cover more on the issue of synthetic organic chemistry.

The development of pharmaceuticals over the globe can be said to have been directed by the mastery of the staff working in the individual organizations.

In the event that an organization has skilful staff individuals, at that point, they are probably going to fly high into the billows of success. Those with poor untrained staff will keep sinking into the remote ocean of sadness. They will keep falling into hands of legal authorities for the absence of consistency and numerous different things. Preparing is vital.

Albeit synthetic organic chemistry is not by any means the only angle that pharmaceutical organizations need to concentrate on, it should not be looked down on. Great Manufacturing Practices (GMP), is one of the strictest therapeutic administrative organization on the planet. It was set up to guarantee that all prescriptions are fabricated in understanding to globally acknowledged principles. All the great pharmaceuticals you see are because of their directions.

At long last, pharmaceutical organizations in the created nations should ascend and give some assistance to those organizations in the immature nations. This is on the grounds that the immature nations don’t have enough ability to create unrivalled quality medications. Science is sweet, so let us take pride in contemplating it constantly, and let us not have a state of mind towards synthetic organic chemistry

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Friedrich Wohler and the Start of Synthetic Organic Chemistry

In 1828 Friedrich Wohler discovered that he could produce urea outside the body without the production of kidney and excretion via urine

He uses inorganic starting materials, to obtain urea he treated silver cyanate with ammonium chloride. This process is the whole idea of synthetic organic chemistry, producing synthesized chemicals using starting materials either organic or inorganic compounds. The discovery led many chemists to produce and see different results, chemical reactions of combined molecules and sometimes seeing the product as medicinal also paved the way for pharmaceutical industry to broaden the list of medicines and vitamins.

Starting Materials for Synthetic Organic Chemistry

There are two different kinds of synthesizing chemicals depending on the starting materials. The very first chemistry organic, which is urea, is a total synthesis process because he used simple inorganic compounds to produce it. Production from inorganic compounds led chemists to see a new route for the targeted molecule – at this point it’s urea. They saw that it could be produced using different compounds, they also focus on seeing new chemical reactions from the by -products of it. The other process is semi-synthesis or partial chemical synthesis which uses organic compounds as a starting material to produce novel compounds with medicinal properties that later on contributed in the pharmaceutical industries. Synthetic organic chemistry is a wide range of chemically produced compounds that we can all see and study up until now.

How can an organic chemical be called synthetic as well?


  • First let’s understand that there is a natural organic chemical where in the chemical compounds are naturally available to us from our ecosystem and varies widely as well.
  • Synthetic organic chemistry is man-made compounds that sometimes imitates natural organic chemicals. Chemists synthesizes these chemicals to produce a synthetic organic chemicals.
  • The two origin of organic chemicals aim one thing as well and the properties are quite similar.

synthetic organic chemistry

A New Direction in Chemistry: Synthetic Organic Chemistry

At around 1820s a chemist named Friedrich Wohler discovered something that forever changed and further made development in chemistry, the figuring out of synthetic organic chemistry.

He wrote a letter to his former mentor, JonsJakob Berzelius, how he produced urea not from a living body in a laboratory through synthetic organic chemistry. They didn’t just analyze existing chemical compounds but they began to synthesize them. This started chemists to also synthesize different smaller molecules from easily accessible compounds and progressed by building-up complex molecular structures.

Components of Synthetic Organic Chemistry

In synthesizing there needs to be a starting material to create another compound, and chemists have tried almost every single compound that they know to create a more complex molecular structure. liquid chromatography must comprise of a carbon atom first and foremost to create an organic compound that could be useful for living sources. They could start up from inorganic materials as well, this is what they need for total synthesis. Through total synthesis the process is to see new chemical reactions and chemical reagents. There is also semi-synthesis or partial chemical synthesis where in the starting materials are those from isolated organic compounds that could then produce other novel compounds that could have medicinal properties. These new compounds from semi-synthesis are usually producing drugs that could also imitate natural organic chemicals.

Difference Between Natural Organic Chemicals and Synthetic Organic Chemistry

  1. Natural organic chemicals are those that’s offer to us by nature itself. It is authentic and is not made by anyone from anything. These chemicals could be from the air we breathe, the soil we step on, the fruits by the trees, or even from the sun.
  2. Synthetic organic chemistry are man-made chemicals that some of it imitates the natural source of chemicals. The vitamins that we get from nature can be produced by synthesizing chemicals having quite the same properties but differing in origin.


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Knowing More of Synthetic Organic Chemistry

Synthetic organic chemistry started way back nineteenth century where chemist Friedrich Wohler discovered the production of urea even outside human bodies using inorganic chemicals

He treated silver cyanate with ammonium chloride that resulted in the production of urea. He immediately told his fellow colleague regarding his discovery. He was able to make a synthetic urea through the process of total synthesis that we’ll tackle later on. This was the first time that synthetic organic chemistry was discovered and made a big impact in the society of chemists. Now, they don’t simply analyze existing molecules but they’re synthesizing them as well, producing a different chemical.

Understanding the idea that an inorganic compound is used for living sources is the main purpose of synthetic organic chemistry. If you look for answers and lists of synthetic organic chemicals there are tons. Ever since it started growing chemists just can’t get enough of analyzing and experimenting. There are also different outcomes that happen when chemists synthesize smaller molecules for a rather complex molecules.

Total Synthesis and Semi-synthesis

Now let’s tackle more on the processes that chemicals go through to develop complex molecules as we’ve said earlier we have the total synthesis and other than that is semi-synthesis.

  • Total synthesis is the process that Friedrich Wohler did for the production of urea. Inorganic compounds are used as starting materials to create a more complex compounds. The results of this have given chemists light in a lot of aspect, they get to see new chemical reactions from the combination of different molecules, they get to check new routes for the synthesis of the targeted molecules – natural products, organic compounds, medicinally important active ingredients. That although these targeted molecules have existing routes it would be of good knowledge to widen the scope of different routes from them.
  • Semi-synthesis or partial chemical synthesis is a process of complete synthesis where in chemicals from isolated natural sources are used as starting material to produce novel compounds that will later on be tried on to animals to see if there are medicinal properties in it.
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Synthetic Organic Chemistry for Chemists

Since the beginning of synthetic organic chemistry it paved way to chemists to the development and impact for synthetic biology.

In the start of nineteenth century chemist Friedrich Wohler then discovered that he can produce urea without using the production from kidney and excretion via urine in the laboratory, he was then so overjoyed and wrote about this to his fellow colleague. This became a stir-up news for everyone around and yet it progresses as well and built countless molecular structure that have been useful even up until now. Synthetic chemistry organic  is still going on since then and producing different kinds of molecular structure for additional chemical reactions or for additional medicinal properties.

What Composes Synthetic Organic Chemistry?

Synthetic organic chemistry is a man-made compound that contains carbon atoms; basically because organic chemicals are deemed organic because of its component, carbon atoms. There are different kind of starting materials for synthetic organic chemistry and it could be inorganic compounds or organic compounds. Organic compounds are those that came from a living source, it could be from humans, from plants, or from animals. While inorganic compounds are those that came from nonliving sources like plastic, rubber, and so on. To make inorganic compounds useful for the use of living source is the idea of synthesizing chemicals.

There are Two Kinds of Synthesis:

  1. Total Synthesis – is the process where in inorganic compounds are the starting materials and they have target molecules that they aim to discover new route for existing ones or for those that doesn’t have routes they’d be able to create a feasible route. They also focus on creating new chemical reaction or chemical reagents.
  2. Semi-Synthesis or Partial Chemical Synthesis – is the process where in they use chemical compounds from organic chemicals to mainly create or produce novel compounds which could have chemical or medical properties that later on be part in the growing pharmaceutical industry as well.

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The History of Synthetic Organic Chemistry

Synthetic Organic Chemistry started out when chemist Friedrich Wohler performed the synthesis of urea in 1828

He excitedly told his former mentor, JonsJakob Berzelius about his new discovery that later on developed the world of organic compound and inorganic compounds. That one synthesis of organic compound led chemists to work on synthesizing different compounds and building-up complex molecules resulting in discovering new route of synthesis for certain targeted molecules that could be medicinally important active ingredients, natural products, or organic products. Synthetic organic chemicals are man-made and contains carbon atoms; since organic compounds are mainly organic because of the carbon atom in its structure.

The Process of Synthetic Organic Chemistry

The processes in doing organic synthetic chemistry involves synthetic analysis and planning. We all know that the process is so much complicated than that but we’ll tackle two ways in choosing starting materials.

  1. Total Synthesis – this uses purely and simple inorganic compounds to create complex molecular structure that results in a completely different compound. This aim is to discover new chemical reactions and chemical reagents. It also aim to find a new route of synthesis for a certain targeted molecule.
  2. Semi-Synthesis or partial chemical synthesis – this uses organic compounds from natural sources as starting material to produce compounds with medicinal properties. Unlike inorganic compounds, organic compounds have higher complexity thus developing compounds that contributes highly in synthetic organic chemistry.

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Synthetic Organic Chemistry vs Natural Organic Chemistry

First, let’s describe natural organic chemistry, as the name itself these are the chemicals that can be found in our nature and present in our everyday lives. The synthetic organic chemistry are chemicals produced by man and could be either helpful towards the development of organic chemistry or helpful as alternative to our natural medicines. Both of them have quite a similarity in their properties but they differ as to where it came from.